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What is it?
Propylene glycol is a solvent and humectant (keeps things moist), and is also used as an additive for its preservative properties. It is widely used in medicines, cosmetics, and in a variety of industries.

How can I avoid it?
Glycerin is an excellent substitute for propylene glycol in many formulations. Extremely sensitive individuals may have a flare-up or dermatitis after oral ingestion of foods or upon the use of oral, intramuscular, or intravenous medications containing propylene glycol.

Skin contact with propylene glycol is required for it to cause a rash. Discontinuation of exposure to products containing propylene glycol should result in improvement and/or resolution of your dermatitis. By law, all products made in the U.S. for topical use have the ingredients listed either on the product package or the box that contains it, so check the labeling of your skin care products for this
ingredient. If there is not enough information ask your pharmacist or retailer, or contact the company directly. At work, request a Safety Data Sheet (SDS) to help identify potential sources of exposure.

Uses:
  • Aircraft de-icing compounds
  • Artificial smoke, fog, and mist machines (fire training, rock concerts, and theater productions)
  • Automotive antifreeze
  • Automotive brake fluid
  • Foods
    • Salad dressing
    • Cake mixes
    • Toppings
    • Cakes
    • Processed vegetables
    • Beverages
    • Shredded coconut
    • Whipped topping mix
    • Cheesecake mix
    • Canned French fried onions
    • Butter flavored popcorn
    • Coffee based drinks
    • Liquid sweeteners
    • Ice cream
    • Baked goods
    • Margarine
    • Nuts
  • Household cleaning products and liquid detergents
  • Wipes
  • Inks
  • Skin care products/Cosmetics
    • Soaps/Cleansers/Household detergents
    • Shampoos/Conditioners
    • Moisturizers/Lotions
    • Make-ups
    • Shaving products
    • Sunscreens
    • Towelettes
    • Deodorants
    • Mouthwash and toothpaste
    • Facial cleansers
  • Medications, prescription and over the counter
    • Oral cough preparations
    • Injectables (intramuscular, intravenous)
    • Anesthetics
    • Antibiotics
    • Benzoyl peroxide preparations
    • Eye/Ear/Nose preparations
    • Lubricant jelly
    • Medical gels (Electro II, electrocardiogram gels, Spectra 360, transcutaneous nerve stimulator gel)
  • Paint
  • Dog food
  • Plastics
  • Tobacco (as humectant)
  • Varnishes and synthetic resins
  • Electronic e-cigarettes/Vaping products

Other names for propylene glycol:
  • 1, 2 dihydroxypropane
  • 1, 2 propanediol
  • Methyl Ethyl Glycol (MEG)
  • 2-Hydroxylpropanol
  • Methylethylene Glycol
  • Propane-1, 2-diol



MC4999-205/2026May

How safe is it?

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