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What is it?
Alpha-methylene-gamma-butyrolactone is the chemical that causes tulip dermatitis. It is most highly concentrated in the bulbs of tulips and lilies. Less is found in the stems, and the least amount of the chemical is found in the petals.

How do I avoid it?
Allergic contact dermatitis is usually seen in workers who have extensive direct contact with tulip or lily bulbs. Florists who handle cut tulip or lily flowers are also at risk of developing allergic contact dermatitis. The amateur gardener and plant fancier rarely develops a sensitivity. Avoidance of tulip and lily bulbs and cut tulip and lily flowers is the obvious way to prevent allergic contact dermatitis. Wearing nitrile latex gloves when handling tulip and lily bulbs and flowers can help prevent dermatitis.

Uses
  • Found in tulip and lily bulbs
  • Facial cleansers
Other names for alpha-methylene-gamma-butyrolactone:
  • Methylene-y-butyrolactone
  • Tuliposide A
  • Tulipalene
  • α-Methylene butyrolactone
  • Calibri-Methylene-γ-butyrolactone
  • Dihydro-3-methylene-2(3H)-furanone
  • Tulipalin A
  • alpha-methylene-γ-butyrolactone
  • Tulipane
Potential cross-reacting/co-reacting substances:
  • Tulipa
  • Alstroemeria (Peruvian Lily) species

Rev01292026

How safe is it?

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