What is it?
Musk ambrette is a synthetic fixative widely used in personal care products as a fragrance ingredient with a potent floral odor. Although it is a rare condition, musk ambrette has been identified as a potential cause of photocontact dermatitis.

How can I avoid it?
Skin contact with musk ambrette is required for it to cause a rash. Discontinuation of exposure to products containing musk ambrette should result in improvement and/or resolution of your dermatitis. By law, all products made in the U.S. for topical use have the ingredient listed either on the product package or the box that contains it. Check the labeling of your skin care products for this substance. If there is not enough information, ask your retailer or call the company directly. At work, request a Safety Data Sheet (SDS) to help identify potential sources of exposure.

Uses:
  • Air fresheners
  • Cleaning products
  • Dentifrices
  • Detergents
  • Food flavoring
  • Skin care products/Cosmetics
    • Deodorants
    • Colognes
    • Hair creams and gels
    • Hairspray
    • Powders
    • Shampoos
    • Shaving products – aftershave and shaving cream
    • Soaps

Other names for musk ambrette:
  • 1-tert-butyl-2-methoxy-4-methyl-3,5-dinitrobenzene
  • 2,6-dinitro-3-methoxy-1-methyl-4-tert-butyl benzene
  • 2,4-dinitro-3-methyl-6-tert-butyl anisole
  • 4-methoxy-1,3-dinitro-2-methyl-5-tert-butyl benzene

Potential cross-reacting/co-reacting substances:
  • Musk Xylene
  • Other fragrances


MC4999-48 (Rev 02-2025)

How safe is it?

Hang tight. We're thinking.